ASC1 and RPS3: new actors in 18S nonfunctional rRNA decay
نویسندگان
چکیده
منابع مشابه
40S subunit dissociation and proteasome-dependent RNA degradation in nonfunctional 25S rRNA decay.
Eukaryotic cells have quality control systems that eliminate nonfunctional rRNAs with deleterious mutations (nonfunctional rRNA decay, NRD). We have previously reported that 25S NRD requires an E3 ubiquitin ligase complex, which is involved in ribosomal ubiquitination. However, the degradation process of nonfunctional ribosomes has remained unknown. Here, using genetic screening, we identified ...
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ژورنال
عنوان ژورنال: RNA
سال: 2017
ISSN: 1355-8382,1469-9001
DOI: 10.1261/rna.061671.117